+169%
Clinical trial sign ups
The increase in average monthly inquiries after launch of search campaigns
<11,000
Total U.S. patient population
Individuals living with Achromatopsia in the United States
2.7x
Increase in monthly inquiries
Average monthly inquiries increased 2.7x with search campaigns
the challenge
AGTC needed to increase clinical trial participation for Achromatopsia treatment while working within an addressable U.S. population of fewer than 11,000 patients.
Traditional broad-reach tactics would create significant waste. The objective was to efficiently connect patients actively seeking information with a clear path to enrollment.
the strategy
Methodically designed for intent.
Search strategy
Targeted keyword strategy focused on high-intent, disease-specific searches
Ad experience
Highly relevant ad copy with sitelink and callout extensions
Landing experience
Optimized sign-up page with clear information and reduced friction
Qualified engagement
Connecting motivated patients with a simple, trusted path to learn more
the proof
Campaign pause proved incrementality.
During a temporary pause in search activity, clinical trial inquiries immediately returned to pre-campaign levels.
When search resumed, inquiry volume increased again.
This confirmed that SEM was directly driving incremental patient recruitment rather than capturing existing demand.
how we delivered results
intelligence
Understand the opportunity.
- • Identified high-intent Achromatopsia search behavior
- • Prioritized disease-specific keywords
- • Mapped patient intent to recruitment goals
activation
Connect with precision.
- • Search engine marketing (SEM)
- • Targeted ad copy
- • Sitelinks & callout extensions
- • Optimized enrollment landing page
measurement
Prove incremental impact.
- • Monitored inquiry volume
- • Campaign pause validated causal impact
- • Clinical trial inquiries returned to baseline during the pause and increased again when campaigns resumed
capabilities demonstrated